new clinical implications of opiate maintenance treatments

نویسندگان

gonzalo haro program of dual pathology. hospital provincial university, castellon, spain; program of dual pathology, hospital provincial university, av dr. clara, 19–12002–castellon de la plana, castellon, spain. tel: +34-964359700, fax: +34-964354301

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منابع مشابه

New Clinical Implications of Opiate Maintenance Treatments

Opiate addiction is a chronic mental illness with severe repercussion in personal and public health. Various medicaments have been subjected to research in order to find a proper treatment, methadone is the most and wide used drug, buprenorphine/naloxone is the most recent ones, but other choices have been proposed such as prescribing heroin (1). The mentioned treatments, are considered as main...

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Maintenance agonist treatments for opiate dependent pregnant women.

BACKGROUND The prevalence of opiate use among pregnant women ranges from 1% to 2% to as much as 21%. Heroin crosses the placenta and pregnant opiate dependent women experience a six fold increase in maternal obstetric complications such as low birth weight, toxaemia, 3rd trimester bleeding, malpresentation, puerperal morbidity, fetal distress and meconium aspiration. Neonatal complications incl...

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18 Clonidine and Lofexidine: New Nonopiate Treatments for Opiate Withdrawal

INTRODUCTION Recent studies (Gold et al, 1978; Washton et al, 1980a) showing that the non-opiate antihypertensive agent, clonidine hydrochloride, suppresses signs and symptoms of opiate withdrawal, have suggested that clonidine and similar drugs might be useful in the clinical management of opiate detoxification. The fact that clonidine is not an opiate drug and does not itself produce addictio...

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Telomere Maintenance Mechanisms in Cancer: Clinical Implications

The presence of immortal cell populations with an up-regulated telomere maintenance mechanism (TMM) is an almost universal characteristic of cancers, whereas normal somatic cells are unable to prevent proliferation-associated telomere shortening and have a limited proliferative potential. TMMs and related aspects of telomere structure and function therefore appear to be ideal targets for the de...

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New Schizophrenia Treatments Address Unmet Clinical Needs.

We present several novel drugs in development for enhancing cognition, treating negative symptoms, and providing improved options for treatment-resistant patients. Drug makers aim to enhance safety profiles and increase patient compliance to therapy.

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Buprenorphine maintenance treatment of opiate dependence: a multicenter, randomized clinical trial.

AIMS To evaluate the safety and efficacy of an 8 mg/day sublingual dose of buprenorphine in the maintenance treatment of heroin addicts by comparison with a 1 mg/day dose over a 16-week treatment period. As a secondary objective, outcomes were determined concurrently for patients treated with two other dose levels. DESIGN Patients were randomized to four dosage groups and treated double-blind...

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عنوان ژورنال:
international journal of high risk behaviors and addiction

جلد ۱، شماره ۲، صفحات ۸۸-۸۹

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